Below are the opening CFP odds, national championship odds and Heisman odds from SportsBetting.com (www.sportsbetting.com):

Notre Dame +19
Alabama -19
Over/Under: 65.5
Moneyline: Notre Dame +750, Alabama -1200

Ohio State +7
Clemson -7
Over/Under: 65
Moneyline: Ohio State +250, Clemson -300

The previous high for a CFP spread was at the 2019 Orange Bowl where Alabama was a 14.5-point against Oklahoma.